A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

Previous work showed that histone ‘readers’, which bind to post-translational modifications on histones, may be upregulated in melanoma and thereby upregulate oncogenes. Given that the histone reader ...

HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing an enzyme in the lysosomes of the roundworm C. elegans, they can extend ...

The upper right portion illustrates viral nucleosome-like particles formed by co-occurring viral histone triplets and singlets. On the lower right, a network depicts distinct types of viral ...

Overproduction of histones also predicted aggressiveness of invasive breast cancer based on an analysis of 13 paraffin-embedded samples. One of the study’s co-first authors, Ye Zheng, PhD, then a ...

In our cells, 6 feet (1.8 m) of DNA gets crammed into chromosomes that fit inside a 6-µm-wide nucleus. The proteins that help pack up that genetic material are histones, which act as spools around ...

The latest chemistry news, including important research advances, business and policy trends, chemical safety practices, career guidance, and more. The work was led by Ian Maze, a neuroepigeneticist ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

Every second, as we breathe, sleep, eat and go about our lives, millions of biochemical reactions are happening in our cells. Among the hurly burly of chemical exchanges are ones that attach small ...

This article was originally featured on Knowable Magazine. Every second, as we breathe, sleep, eat and go about our lives, millions of biochemical reactions are happening in our cells. Among the hurly ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...