The NFL wraps up the 2025-26 regular season this weekend as Week 18 will finalize the 2026 playoff bracket and the first 18 picks of the 2026 NFL Draft. We’ll see an assortment of teams resting players in preparation for the playoffs, as teams without a chance at a bye are looking to get ready for next weekend’s Wild Card round.

Overall picks to win: 8-8 in Week 17 (173-82-1 for the season) Picks to win with 1-5 confidence: 4-7 (103-64-1) Picks to win with 6-10 confidence: 4-1 (70-18) Overall to cover the spread: 9-6-1 (130-117-9) Cover-the-spread picks with 1-5 confidence: 8-4-1 (107-93-8) Cover-the-spread picks with 6-10 confidence: 1-2 (23-23-1)

The Falcons are 3.5-point favorites in the latest Falcons vs. Saints odds from DraftKings, while the over/under for total points scored is 44.5. Before you lock in your own Falcons vs. Saints picks, make sure you see the top NFL picks from the SportsLine Projection Model,

Preview the Houston Texans' NFL week 18 matchup with the Colts, including betting odds, tips, trends, and game information.