When a cell is able to take up free DNA or RNA, it is termed “competent”. Some cell types or microbial species, such as Bacillus subtilis, 11 are naturally competent and they can be induced to uptake ...

Knockout mice are animals that have been genetically modified for so that one or more genes are not expressed, or “knocked out.” Studies are then carried out on the mice to determine what the effects ...

Pulsed electrical fields can be used to introduce DNA into a wide variety of animal cells 1,2. Electroporation works well with cell lines that are refractive to other techniques, such as calcium ...

Because it is versatile—it works with any cell, any organism—electroporation is uniquely advantageous. Electroporation uses an electrical pulse to introduce new species, usually polar molecules, into ...

RNA interference (RNAi), an important tool for gene expression and gene function analyses, can be induced by the introduction of sequence-specific small interfering RNAs (siRNAs) into cells. For an ...

Cell therapy is an emerging novel treatment option for an array of diseases, ranging from genetic disorders to cancer. As the cell therapy field expands, there is a growing demand for safe and ...

Unleash the power of electroporation with the Invitrogen Neon NxT Electroporation System. Join us for an insightful webinar where we demystify the basics of electroporation and guide you on how to ...

Recognized as the leader in nucleic acid delivery technologies, Mirus Bio announces the first instrument added to their product portfolio, the Ingenio® EZporator® Electroporation System. Recognized as ...

Electroporation is a technology used to increase the permeability of cell membranes. It is used to induce cells to take up a variety of substances, including chemicals, drugs, and DNA. When cells take ...

Gene-based immunotherapy for cancer is limited by the lack of safe, efficient, reproducible, and titratable delivery methods. Direct injection of DNA into tissue, although safer than viral vectors, ...