An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study ...

Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

What scientists long believed were knots in DNA may actually be persistent twists formed during nanopore analysis, revealing ...

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about 0.01 mm in size, it must be tightly folded. DNA wraps around proteins call ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...