A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Throughout the course of our lives, DNA can break in response to natural and environmental factors. However, our bodies have dedicated enzymes and pathways which can repair our broken DNA back ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

The following Q&A is an edited version of the podcast. What are enzymes and how they operate? Enzymes are the molecules in our bodies that facilitate reactions. They perform this function at their ...

There are many health problems that can be traced back to errors in the genetic code. There are also many potential benefits to genetic engineering outside of healthcare. Nature has already found ways ...

As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, ...