A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
A central tenet of biology may need updating given new measurements of start codons. For decades, scientists working with genetic material have labored with a few basic rules in mind. To start, DNA is ...
Cells working with an expanded genetic code could make more diverse medicines. A new study shows scientists are within striking distance. One of modern biologists' most ambitious goals is to learn how ...
A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a long-held rule of biology.
The choice of codons can influence local translation kinetics during protein synthesis. Whether codon preference is linked to cotranslational regulation of polypeptide folding remains unclear. Here, ...
Synonymous codons are used non-randomly in the transcriptome to shape multiple aspects of translation. Optimal codons are associated with more efficient translation and correspond to cognate tRNA ...
DNA is admired for its perfection as a programmable information molecule: it uses repeating polymerization chemistry to link four nucleotide building blocks (adenine, cytosine, guanine, and thymine) ...
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