Vibrio cholerae presents a unique model of bacterial genome organisation through its bipartite genome, comprising two distinct chromosomes that replicate in a carefully orchestrated manner. The ...

The initiation of chromosome replication is exquisitely regulated in both time and location. It has been estimated that there are 200-400 autosomal replication sequence elements (ARSs) in the yeast ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

A new study has found that the photosynthetic bacterium Synechococcus elongatus uses a circadian clock to precisely time DNA replication, and that interrupting this circadian rhythm prevents ...

Extra chromosomes, found in some fish, contain copied genes that don’t work but can still impact the organism. Research shows ...

Jenny Graves is a Friend of The Conversation. Neanderthals, the closest cousins of modern humans, lived in parts of Europe and Asia until their extinction some 30,000 years ago. Genetic studies are ...